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10.3390/ijms20071593 Int J Mol Sci

The glutathione transferase inhibitor 6-(7-nitro-2, 1, 3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) increases temozolomide efficacy against malignant melanoma

Duration of benefits differs between methods : IV glutathione provides immediate peak plasma concentrations but benefits typically fade within 6 months of discontinuation, while oral supplementation offers sustained effects with regular daily dosing